Multicomponent exercise intervention

Intervention

2 papers study it5 findings

  • 2 independent labs in 2 countries
  • Funders: Agencia Estatal de Investigación and 8 more
  • Human trial2

Outcomes

5

NfL

no changein humans1

1 study
  1. Multicomponent exercise intervention has no effect on NfL in humans.

    “NfL concentration did not change in either group.”

    Human trialserum2 yearsn = 45

    Effects of a 2-year exercise training on neuromuscular system health in older individuals with low muscle function

    Journal of cachexia, sarcopenia and muscleJan 28, 2023

More on NfL

Short Physical Performance Battery

upin humans1

1 study
  1. Multicomponent exercise intervention improves Short Physical Performance Battery in humans (P = 0.007).

    “MCI showed preserved VL architecture (PA, Lf) despite a reduced CSA (-8.4%, P < 0.001), accompanied by maintained CAF concentration and ameliorated overall SPPB performance (P = 0.007).”

    Human trial2 yearsn = 24

    Effects of a 2-year exercise training on neuromuscular system health in older individuals with low muscle function

    Journal of cachexia, sarcopenia and muscleJan 28, 2023

More on Short Physical Performance Battery

Emergency visits

downin humans1

1 study
  1. Multicomponent exercise intervention decreases emergency visits in humans.

    “The Real-Life intervention led to a significant reduction in the number of falls, visits to the primary care centers and emergency visits when compared to the results of our previously published Clinical Trial.”

    Human trialwhen compared to the results of our previously published Clinical Trialn = 50

    Real-Life Outcomes of a Multicomponent Exercise Intervention in Community-Dwelling Frail Older Adults and Its Association with Nutritional-Related Factors

    NutrientsDec 3, 2022

Falls

downin humans1

1 study
  1. Multicomponent exercise intervention decreases falls in humans.

    “The Real-Life intervention led to a significant reduction in the number of falls, visits to the primary care centers and emergency visits when compared to the results of our previously published Clinical Trial.”

    Human trialwhen compared to the results of our previously published Clinical Trialn = 50

    Real-Life Outcomes of a Multicomponent Exercise Intervention in Community-Dwelling Frail Older Adults and Its Association with Nutritional-Related Factors

    NutrientsDec 3, 2022

Frailty

downin humans1

1 study
  1. Multicomponent exercise intervention decreases frailty in humans.

    “We found higher improvements in the Real-Life exercise intervention vs. the Clinical Trial in functional parameters, such as Fried's frailty criteria, Tinetti, Barthel and Lawton & Brody scales.”

    Human trialvs. Clinical Trial (NCT02331459)n = 50

    Real-Life Outcomes of a Multicomponent Exercise Intervention in Community-Dwelling Frail Older Adults and Its Association with Nutritional-Related Factors

    NutrientsDec 3, 2022

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