Monascin

1. Monascin increases survival rate in worms.

   “Monascin-treated C. elegans showed an increased survival rate during oxidative stress and heat stress treatments compared to untreated controls.”

   Model organismsduring oxidative stress and heat stress treatments

   Monascin from red mold dioscorea as a novel antidiabetic and antioxidative stress agent in rats and Caenorhabditis elegans

   Free radical biology & medicine·12 Oct 2011

1. Monascin extends lifespan in worms.

   “monascin extended the life span under high-glucose conditions and enhanced expression of small heat shock protein (sHSP-16.2), superoxide dismutase (SOD-3), and glutathione S-transferase (GST-4) in C. elegans.”

   Model organismsunder high-glucose conditions

   Monascin from red mold dioscorea as a novel antidiabetic and antioxidative stress agent in rats and Caenorhabditis elegans

   Free radical biology & medicine·12 Oct 2011

1. Monascin decreases blood glucose in rats.

   “significantly lowered blood glucose, serum triglyceride, and total cholesterol and higher high-density lipoprotein levels were observed in monascin-treated rats.”

   Animalsin STZ-induced diabetic rats30 mg/kg/day8 weeks

   Monascin from red mold dioscorea as a novel antidiabetic and antioxidative stress agent in rats and Caenorhabditis elegans

   Free radical biology & medicine·12 Oct 2011

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