Momordica charantia saponins

1. Momordica charantia saponins extend lifespan in worms.

   “extend the lifespan of N2 and CL2006 worms under paraquat-induced oxidative stress”

   Model organismsunder paraquat-induced oxidative stress

   Responses of bitter melon saponins to oxidative stress and aging via the IIS pathway linked with sir-2.1 and hlh-30

   Journal of food biochemistry·Oct 13, 2022

1. Momordica charantia saponins inhibit oxidative stress and ROS signaling in worms.

   “BMS inhibited the ROS accumulation”

   Model organismsin C. elegans

   Responses of bitter melon saponins to oxidative stress and aging via the IIS pathway linked with sir-2.1 and hlh-30

   Journal of food biochemistry·Oct 13, 2022

More on Oxidative stress and ROS signaling

1. Momordica charantia saponins decrease muscle fiber damage in worms.

   “delaying the muscle fiber damage with age in Caenorhabditis elegans”

   Model organismswith age

   Responses of bitter melon saponins to oxidative stress and aging via the IIS pathway linked with sir-2.1 and hlh-30

   Journal of food biochemistry·Oct 13, 2022

1. Momordica charantia saponins improve physical function in worms.

   “bitter melon saponins could strengthen locomotive activities (body bend and head thrashing) accompanied by delaying the muscle fiber damage with age in Caenorhabditis elegans”

   Model organismswith age

   Responses of bitter melon saponins to oxidative stress and aging via the IIS pathway linked with sir-2.1 and hlh-30

   Journal of food biochemistry·Oct 13, 2022