Modified otago exercise program

Intervention

1 paper3 findings

  • 1 lab in 1 country
  • Funders: Augusta University and 1 more
  • Human trial1

Outcomes

3

Global DNA methylation

no changein humans1

1 study
  1. Modified otago exercise program has no effect on global DNA methylation in humans.

    “Intention-to-treat and per-protocol analyses revealed no statistically significant between-group differences in any biomarker.”

    Human trialpeople living with dementia6 monthsn = 42

    Preliminary effects of a modified Otago Exercise Program on metabolic, cellular, and epigenetic biomarkers in people living with dementia: A pilot randomized controlled trial

    Molecular and cellular neurosciences18 Mar 2026

More on Global DNA methylation

Telomere length

no changein humans1

1 study
  1. Modified otago exercise program has no effect on telomere length in humans (8.00 ± 0.90 to 7.90 ± 0.90 kb).

    “there was no change in the exercise group (8.00 ± 0.90 to 7.90 ± 0.90 kb) from baseline to 6 months”

    Human trialpeople living with dementia6 monthsn = 42

    Preliminary effects of a modified Otago Exercise Program on metabolic, cellular, and epigenetic biomarkers in people living with dementia: A pilot randomized controlled trial

    Molecular and cellular neurosciences18 Mar 2026

More on Telomere length

Kynurenine

no changein humans1

1 study
  1. Modified otago exercise program has no effect on kynurenine in humans.

    “Intention-to-treat and per-protocol analyses revealed no statistically significant between-group differences in any biomarker.”

    Human trialpeople living with dementia6 monthsn = 42

    Preliminary effects of a modified Otago Exercise Program on metabolic, cellular, and epigenetic biomarkers in people living with dementia: A pilot randomized controlled trial

    Molecular and cellular neurosciences18 Mar 2026

More on Kynurenine

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