Mnp@cd26@17d
1 paper3 findings
- 1 lab in 1 country
- Funders: Agencia Estatal de Investigación and 8 more
- Cells1
Outcomes
3Hemolysis
no changein human cells1
1 study
Hemolysis
no changein human cells1
Mnp@cd26@17d has no effect on hemolysis in human cells.
“As 24 h treatment with MNP@CD26@17D did not induce hemolysis in human erythrocytes in vitro”
Cellsin vitro24 h
ACS biomaterials science & engineeringDec 4, 2024
Ferroptosis
upin human cells1
1 study
Ferroptosis
upin human cells1
Mnp@cd26@17d induces ferroptosis in human cells.
“A dual response to MNP@CD26@17D stimulation in senescent cells was revealed, namely, apoptosis-based early response (2 h treatment) and ferroptosis-based late response (24 h treatment).”
Cellsin oxidative stress-induced senescent human fibroblasts and drug-induced senescent cutaneous squamous cell carcinoma cells
ACS biomaterials science & engineeringDec 4, 2024
Apoptosis
upin human cells1
1 study
Apoptosis
upin human cells1
Mnp@cd26@17d induces apoptosis in human cells.
“A dual response to MNP@CD26@17D stimulation in senescent cells was revealed, namely, apoptosis-based early response (2 h treatment) and ferroptosis-based late response (24 h treatment).”
Cellsin oxidative stress-induced senescent human fibroblasts and drug-induced senescent cutaneous squamous cell carcinoma cells
ACS biomaterials science & engineeringDec 4, 2024
Latest
ACS Biomaterials Science & Engineering
Design of a Magnetic Nanoplatform Based on CD26 Targeting and HSP90 Inhibition for Apoptosis and Ferroptosis-Mediated Elimination of Senescent Cells
Experiments in human cellsInterventions