Minimally invasive surgery

Minimally invasive surgery has been studied in 10 papers since 2021: 10 observational studies in people; 4 in the past year. The newest paper, Mar 19, 2026: “Frailty and Days at Home After Ovarian Cancer Surgery- A Patient-Centered Outcome for Older Adults”.

Exposure

10 papers study it13 findingsUpdated

See all 10

“At 6 months follow-up, the minimally invasive technique contributed to significantly better functional recovery as measured by the Parker (p < 0.05) and Katz scores (p < 0.05).”
Periprosthetic fracture around total knee arthroplasty: What are the advantages of minimal-invasive surgery?Injury2024doi:10.1016/j.injury.2024.111351

None of its findings points the other way.

  • 8 independent labs in 6 countries
  • Funders: National Institute of Child Health and Human Development and 1 more
  • 1 of 13 findings with company ties
  • Humans10

What did studies of Minimally invasive surgery find?

7

Studies of Minimally invasive surgery measured 7 outcomes; the most studied are postoperative complications (2 studies), functional recovery (2) and 90-day hospital readmission (1).

Postoperative complications

downin humans2

2 studies
  1. Minimally invasive surgery decreases postoperative complications in humans.

    “severe postoperative complications were significantly better in the MIS group.”

    Humanselective surgery for gastrointestinal and hepatobiliary-pancreatic tumors

    Effect of minimally invasive surgery on activities of daily living in elderly patients aged ≥ 80 years with gastrointestinal and hepatobiliary-pancreatic cancers: a propensity score-matched analysis

    Surgical endoscopy

  2. Minimally invasive surgery decreases postoperative complications in humans.

    “minimally invasive techniques were associated with improved functional recovery and fewer complications than traditional methods”

    Humanselderly hip fracture12 monthsn = 120

    Prospective cohort study on recovery outcomes in elderly hip fracture patients using minimally invasive techniques

    Bioinformation

Functional recovery

upin humans2

2 studies
  1. Minimally invasive surgery improves functional recovery in humans.

    “minimally invasive techniques were associated with improved functional recovery and fewer complications than traditional methods”

    Humanselderly hip fracture12 monthsn = 120

    Prospective cohort study on recovery outcomes in elderly hip fracture patients using minimally invasive techniques

    Bioinformation

  2. Minimally invasive surgery improves functional recovery in humans (p < 0.05).

    “At 6 months follow-up, the minimally invasive technique contributed to significantly better functional recovery as measured by the Parker (p < 0.05) and Katz scores (p < 0.05).”

    Human trial6 months

    Periprosthetic fracture around total knee arthroplasty: What are the advantages of minimal-invasive surgery?

    Injury

90-day hospital readmission

downin humans1

1 study
  1. Minimally invasive surgery decreases 90-day hospital readmission in humans (16.6% vs. 22.3%, P = 0.11).

    “The 90-day readmission rate was also lower in the MIS groups (16.6% vs. 22.3%, P = 0.11).”

    Humanselective surgery for gastrointestinal and hepatobiliary-pancreatic tumors

    Effect of minimally invasive surgery on activities of daily living in elderly patients aged ≥ 80 years with gastrointestinal and hepatobiliary-pancreatic cancers: a propensity score-matched analysis

    Surgical endoscopy

Severe activities of daily living decline

downin humans1

1 study
  1. Minimally invasive surgery decreases severe activities of daily living decline in humans (5.7% vs. 9.5%, P = 0.11).

    “Severe postoperative ADL decline was lower in the MIS than in the open groups (5.7% vs. 9.5%, P = 0.11).”

    Humanselective surgery for gastrointestinal and hepatobiliary-pancreatic tumors

    Effect of minimally invasive surgery on activities of daily living in elderly patients aged ≥ 80 years with gastrointestinal and hepatobiliary-pancreatic cancers: a propensity score-matched analysis

    Surgical endoscopy

Activities of daily living decline

no changein humans1

1 study
  1. Minimally invasive surgery has no effect on activities of daily living decline in humans (17.3% vs. 19.4%, P = 0.59).

    “postoperative ADL decline occurred in 17.3% and 19.4% of patients in the open and MIS groups, respectively (P = 0.59).”

    Humanselective surgery for gastrointestinal and hepatobiliary-pancreatic tumors

    Effect of minimally invasive surgery on activities of daily living in elderly patients aged ≥ 80 years with gastrointestinal and hepatobiliary-pancreatic cancers: a propensity score-matched analysis

    Surgical endoscopy

Time-at-home

upin humans1HR 0.71

1 study
  1. Minimally invasive surgery improves time-at-home in humans (54.9% vs 41.2%, HR 0.71, 95% CI 0.68-0.75).

    “The MIS group had higher probability ofhigh time-at-home than open surgery with 54.9% (95% CI 53.6%-56.1%) versus 41.2% (95% CI 40.1%-42.3%) at 5years (hazard ratio 0.71, 95% CI 0.68-0.75).”

    Humanscolorectal cancer resection5 yearsn = 16,479

    Minimally Invasive Compared to Open Colorectal Cancer Resection for Older Adults: A Population-based Analysis of Long-term Functional Outcomes

    Annals of surgery

Homecare use

downin humans1HR 0.87

1 study
  1. Minimally invasive surgery decreases homecare use in humans (HR 0.87, 95% CI 0.83-0.92).

    “The MIS group had lower homecare use than the open group with 22.3% versus 31.6% at 6 months and 14.8% versus 19.4% at 1 year [hazard ratio 0.87,95% confidence interval (CI) 0.83-0.92].”

    Humanscolorectal cancer resection5 yearsn = 16,479

    Minimally Invasive Compared to Open Colorectal Cancer Resection for Older Adults: A Population-based Analysis of Long-term Functional Outcomes

    Annals of surgery

What is Minimally invasive surgery linked with?

3

Studies link Minimally invasive surgery with 3 measures, most often loss of independence (2 studies), days at home (1) and postoperative complications (1).

Loss of independence

downin humans2

2 studies
  1. Minimally invasive surgery lowers the risk of loss of independence in humans (P = 0.040).

    “Minimally invasive surgery reduces the risk of loss of independence after pancreatoduodenectomy in elderly patients”

    Humansafter pancreatoduodenectomy

    Minimally invasive surgery reduces the risk of loss of independence after pancreatoduodenectomy in elderly patients

    Surgical endoscopy

  2. Minimally invasive surgery lowers the risk of loss of independence in humans (9.4% vs 30.8%, P = .050).

    “The incidence of postoperative loss of independence was 9.4% in the frail patients who underwent minimally invasive surgery (MIS) and 30.8% in those who underwent open surgery”

    Humansfrail patients undergoing hepatopancreaticobiliary surgery

    Risk assessment for loss of independence after hepatopancreaticobiliary surgery in the elderly: a prospective multicenter study

    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract

Days at home

upin humans1

1 study
  1. Minimally invasive surgery is associated with days at home in humans (+28 days; 95% CI, 24 to 33; P<.001).

    “Minimally invasive surgery (MIS) was associated with higher DAH (+28 days; 95% CI, 24 to 33; P<.001).”

    Humansovarian cancer surgeryfemalesn = 7,348

    Frailty and Days at Home After Ovarian Cancer Surgery- A Patient-Centered Outcome for Older Adults

    Journal of the National Comprehensive Cancer Network : JNCCN

Postoperative complications

downin humans1

1 study
  1. Minimally invasive surgery lowers the risk of postoperative complications in humans (Laparoscopic: 1%, Robotic: 2.6%, Open: 4.6%; p < 0.001).

    “Minimally invasive hepatectomies had a lower rate of Clavien-Dindo grade IV complications for non-frail”

    Humansin post-hepatectomy patientsn = 24,150

    The impact of minimally invasive surgery and frailty on post-hepatectomy outcomes

    HPB : the official journal of the International Hepato Pancreato Biliary Association

Latest

Nov 2025: 0Dec 2025: 2Jan 2026: 0Feb 2026: 0Mar 2026: 2Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 04 papers in 12 months