Microbiota clearance

Exposure

1 paper1 finding

  • 1 lab in 1 country
  • Funders: National Natural Science Foundation of China and 1 more
  • Animals1

Outcomes

1

Dextromethorphan systemic exposure

downin mice1

1 study
  1. Microbiota clearance decreases dextromethorphan systemic exposure in mice.

    “age-related increase in DEX exposure in the old mice could be reversed by clearance of microbiota”

    Animalsclearance of microbiota

    Gut microbiota influence pharmacokinetics variability in aging mice: Effects vary from drug to drug

    Drug metabolism and disposition: the biological fate of chemicals21 Jan 2026

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