Metal mixture exposure

1. Metal mixture exposure is associated with mild cognitive impairment in humans (OR 1.07, 95% CI 0.95–1.20 per quartile increase).

   “a quartile rise in metal mixture corresponded to 7% higher MCI odds [OR=1.07, 95% CI: 0.95, 1.20], with no statistically significant association observed.”

   HumansAnhui Yangtze River residentsper quartile increase in metal mixture

   Modifying effects of Folate, Vitamin B₁₂ Status on associations between metals exposure and mild cognitive impairment incidence: A prospective cohort study of adults living along the Yangtze River, China

   Environmental pollution (Barking, Essex : 1987)·16 Oct 2026

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1. Metal mixture exposure raises the risk of dyslipidemia in humans.

   “both individual and combined exposures to Cr, Cd, Pb, and Mn significantly affected dyslipidemia”

   Humansn = 403

   Complex metal interaction networks and the mediating role of biological aging in dyslipidemia

   Environmental pollution (Barking, Essex : 1987)·11 Mar 2025

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