Low oxygen culture

1. Low oxygen culture decreases CDKN1B in rat cells.

   “downregulation of the cell cycle inhibitor p27Kip1”

   Cellssatellite cells derived from 31-month-old ratsskeletal muscleapproximately 3% O2

   Culture in low levels of oxygen enhances in vitro proliferation potential of satellite cells from old skeletal muscles

   Cellular and molecular life sciences : CMLS·1 Jul 2001

More on CDKN1B

1. Low oxygen culture activates AKT1 in rat cells.

   “activation of cell cycle progression factors, phosphorylation of Akt, and downregulation of the cell cycle inhibitor p27Kip1”

   Cellssatellite cells derived from 31-month-old ratsskeletal muscleapproximately 3% O2

   Culture in low levels of oxygen enhances in vitro proliferation potential of satellite cells from old skeletal muscles

   Cellular and molecular life sciences : CMLS·1 Jul 2001

More on AKT1

1. Low oxygen culture increases proliferation potential in rat cells.

   “Under the lowered O2 conditions, we noted a remarkable increase in the percentage of large-sized colonies”

   Cellssatellite cells derived from 31-month-old ratsskeletal muscleapproximately 3% O2

   Culture in low levels of oxygen enhances in vitro proliferation potential of satellite cells from old skeletal muscles

   Cellular and molecular life sciences : CMLS·1 Jul 2001