Local low-frequency vibration

Intervention1 paper3 findings

  • Animals1

Outcomes

3

PTX3

downin rats1Very low certainty

1 study
  1. Local low-frequency vibration decreases PTX3 in rats.

    Animalshyperglycemic full-thickness wound model52 Hzskintwice daily for 40 minn = 5

    Local Low-Frequency Vibration Enhances Wound-Healing and Modulates Cellular Senescence in Tissues and Exudates in a Hyperglycemic Rat Model · The Journal of dermatology · 2 Sep 2026

PTX3 →

p53–p21 pathway

downin rats1Very low certainty

1 study
  1. Local low-frequency vibration decreases p53–p21 pathway in rats.

    Animalshyperglycemic full-thickness wound model52 Hzskintwice daily for 40 minn = 5

    Local Low-Frequency Vibration Enhances Wound-Healing and Modulates Cellular Senescence in Tissues and Exudates in a Hyperglycemic Rat Model · The Journal of dermatology · 2 Sep 2026

p53–p21 pathway →

Wound closure

upin rats1Very low certainty

1 study
  1. Local low-frequency vibration improves wound closure in rats.

    Animalshyperglycemic full-thickness wound model52 Hzskintwice daily for 40 minn = 5

    Local Low-Frequency Vibration Enhances Wound-Healing and Modulates Cellular Senescence in Tissues and Exudates in a Hyperglycemic Rat Model · The Journal of dermatology · 2 Sep 2026

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