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Litter crowding

Exposure

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Ellison Medical Foundation and 2 more
  • Animals1

Outcomes

1

ATF4

upin mice1

1 study

  1. Litter crowding increases ATF4 in mice.

    “elevated ATF4 levels, and elevation of ATF4-dependent proteins and mRNAs, in liver of mice treated with acarbose or rapamycin, calorically restricted mice, methionine-restricted mice, and mice subjected to litter crowding.”

    Animalsliver

    ATF4 activity: a common feature shared by many kinds of slow-aging mice

    Aging cell26 Aug 2014

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