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Ligustilide

1 paper

PubChem 5319022 ChEBI 68232

Latest

Frontiers in Aging·12 Jul

Pathobiology of the Klotho Antiaging Protein and Therapeutic Considerations

ReviewKL

Related

Biguanides1
FGF231
FGFR11
FOXO signalling1
Hypercalcemia1
Insulin/IGF-1 signalling1
KL1
Klotho1
Klotho–FGF23 axis1
NF-κB signalling1
NRF2–KEAP1 antioxidant response1
TGF-β signalling1
Wnt/β-catenin signalling1
Astaxanthin1
Atrophy1
Cardiac hypertrophy1

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ER-100 glaucoma trial findings support testing higher dosesTrialsLongevity.Technology and 4 more

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Newer cohorts of older Europeans show slower intrinsic capacity lossResearchThe Lancet Healthy Longevity

Trials

AKG and Brain Health in AgingPhase 2Registered 6 Oct 2026, University of Oklahoma Safety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)Phase 1Registered 2 Oct 2026, Vinmec Research Institute of Stem Cell and Gene Technology AI-Based Conversational Social Support for Older Adults With Heart FailureRegistered 7 Oct 2026, Chang Gung University of Science and Technology

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Nicotinamide ribosideInterventionNicotinamide riboside did not improve early Parkinson disease PregnancyExposureEstimated brain-age gap rises by three years in pregnancy TERTGeneBlood-cell telomerase delays premature aging in zebrafish Vitamin DInterventionSevere vitamin D deficiency is linked to higher death rates Ketogenic dietInterventionKetogenic diet improved heart function in aged mice Immune responseProcessImmune cell ratio linked to healthy and disease-related aging

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Mechanisms241 Interventions426 Biomarkers410 Populations547 AI & data167 Industry & policy18

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