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Lifetime trauma exposure

Exposure

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: National Center for Advancing Translational Sciences and 3 more
  • 2 of 2 findings with company ties
  • Humans1

Outcomes

2

DunedinPACE

upin humans1

1 study

  1. Lifetime trauma exposure increases DunedinPACE in humans (B (SE) = 0.33 (0.11), p = .003).

    “DunedinPACE, 1: B (SE) = 0.23 (0.12), p = .07, 2+: B (SE) = 0.33 (0.11), p = .003”

    Humans≥ 2 lifetime traumas vs no trauma exposurewhole bloodfemales

    Lifetime trauma exposure and accelerated epigenetic aging among midlife women

    Health psychology : official journal of the Division of Health Psychology, American Psychological Association16 Jun 2025

More on DunedinPACE

GrimAge

upin humans1

1 study

  1. Lifetime trauma exposure increases GrimAge in humans (B (SE) = 0.39 (0.13), p = .004).

    “those with ≥ 2 lifetime traumas had older epigenetic age, GrimAge, 1: B (SE) = 0.15 (0.15), p = .31, 2+: B (SE) = 0.39 (0.13), p = .004”

    Humans≥ 2 lifetime traumas vs no trauma exposurewhole bloodfemales

    Lifetime trauma exposure and accelerated epigenetic aging among midlife women

    Health psychology : official journal of the Division of Health Psychology, American Psychological Association16 Jun 2025

More on GrimAge

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