Lentivirus-fto

1 paper3 findings

1 lab in 1 country

Funder: Tobacco Related Disease Research Program

Animals1

Outcomes

3

Cardiac hypertrophy

downin rats1

1 study

Lentivirus-fto decreases cardiac hypertrophy in rats.
“overexpression of FTO via FTO lentivirus (Lenti-FTO) reversed GDM-induced hypertrophy, cardiac senescence, and dysfunction.”
Animalsin offspring of Sprague-Dawley rats with GDMheart
FTO-dependent m6A methylation mediates gestational diabetes mellitus-induced offspring cardiac senescent hypertrophy and dysfunction
iScience5 Dec 2025

Cardiac senescence

downin rats1

1 study

Lentivirus-fto decreases cardiac senescence in rats.
“overexpression of FTO via FTO lentivirus (Lenti-FTO) reversed GDM-induced hypertrophy, cardiac senescence, and dysfunction.”
Animalsin offspring of Sprague-Dawley rats with GDMheart
FTO-dependent m6A methylation mediates gestational diabetes mellitus-induced offspring cardiac senescent hypertrophy and dysfunction
iScience5 Dec 2025

Cardiac dysfunction

downin rats1

1 study

Lentivirus-fto decreases cardiac dysfunction in rats.
“overexpression of FTO via FTO lentivirus (Lenti-FTO) reversed GDM-induced hypertrophy, cardiac senescence, and dysfunction.”
Animalsin offspring of Sprague-Dawley rats with GDMheart
FTO-dependent m6A methylation mediates gestational diabetes mellitus-induced offspring cardiac senescent hypertrophy and dysfunction
iScience5 Dec 2025

Latest

1 in 12 months

iScience9 Jan

FTO-dependent m6A methylation mediates gestational diabetes mellitus-induced offspring cardiac senescent hypertrophy and dysfunction

Experiments in ratsCellular senescence