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Lentivirus carrying HMGB2

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: Chinese Academy of Sciences and 8 more
  • 1 of 1 finding with company ties
  • Cells1

Associations

1

Osteoarthritis

downin mice1

1 study

  1. Lentivirus carrying HMGB2 lowers the risk of osteoarthritis in mice.

    “gene therapy with lentiviruses carrying SOX5 or HMGB2 rejuvenated cartilage and alleviated osteoarthritis in aged mice.”

    Animalslentiviruses carrying HMGB2cartilage

    Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation

    Cell stem cellOct 12, 2023

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