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KB1541

Intervention

1 paper studies it2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Ministry of Science, ICT and Future Planning and 2 more
  • Cells1

Outcomes

2

Oxidative phosphorylation

upin cells1

1 study

  1. KB1541 increases oxidative phosphorylation in cells.

    “This phosphorylation increased ATP synthase 5 alpha/beta dimerization, which in turn promoted ATP production through increased oxidative phosphorylation (OXPHOS) efficiency.”

    Cellsby phosphorylating 14-3-3ζ at serine 58

    Targeting regulation of ATP synthase 5 alpha/beta dimerization alleviates senescence

    AgingJan 30, 2022

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Cellular senescence

downin cells1

1 study

  1. KB1541 decreases cellular senescence in cells.

    “identified an oxazoloquinoline analog (KB1541) designed to inhibit IL-33 signaling pathway.”

    Cellssenescence

    Targeting regulation of ATP synthase 5 alpha/beta dimerization alleviates senescence

    AgingJan 30, 2022

More on Cellular senescence

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