Kaempferol tetrasaccharide

Kaempferol tetrasaccharide has been studied in 1 paper since 2022: 1 trial in people. The newest paper, Oct 14, 2022: “Kaempferol tetrasaccharides restore skin atrophy via PDK1 inhibition in human skin cells and tissues: Bench and clinical studies”.

Intervention

1 paper studies it4 findingsUpdated

“Clinical enhancement in skin appearance was noted in multiple participants”
Kaempferol tetrasaccharides restore skin atrophy via PDK1 inhibition in human skin cells and tissues: Bench and clinical studiesBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie2022doi:10.1016/j.biopha.2022.113864

None of its findings points the other way.

  • 1 lab in 1 country
  • 4 of 4 findings with company ties
  • Human trial1

What did studies of Kaempferol tetrasaccharide find?

4

Studies of Kaempferol tetrasaccharide measured 4 outcomes; the most studied are extracellular matrix structure (1 study), skin appearance (1) and collagen fibers (1).

Extracellular matrix structure

upin humans1

1 study
  1. Kaempferol tetrasaccharide improves extracellular matrix structure in humans.

    “immunohistochemical study revealed improvement in the histological appearance of skin tissue and extracellular matrix”

    Human trialskin

    Kaempferol tetrasaccharides restore skin atrophy via PDK1 inhibition in human skin cells and tissues: Bench and clinical studies

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Skin appearance

upin humans1

1 study
  1. Kaempferol tetrasaccharide improves skin appearance in humans.

    “Clinical enhancement in skin appearance was noted in multiple participants”

    Human trialskin

    Kaempferol tetrasaccharides restore skin atrophy via PDK1 inhibition in human skin cells and tissues: Bench and clinical studies

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Collagen fibers

upin human cells1

1 study
  1. Kaempferol tetrasaccharide increases collagen fibers in human cells.

    “an increase in collagen fiber was observed in the skin cell and human skin equivalent”

    Cellsskin

    Kaempferol tetrasaccharides restore skin atrophy via PDK1 inhibition in human skin cells and tissues: Bench and clinical studies

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

More on Collagen fibers

Cellular senescence

downin human cells1

1 study
  1. Kaempferol tetrasaccharide decreases cellular senescence in human cells.

    “Natural phytochemical kaempferol tetrasaccharides resulted in a significant reduction in cellular senescence”

    Cellsskin

    Kaempferol tetrasaccharides restore skin atrophy via PDK1 inhibition in human skin cells and tissues: Bench and clinical studies

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

More on Cellular senescence

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