Juvenile hormone iii

Juvenile hormone iii shortens lifespan in flies.

“the JH mimic methoprene and JH III can fully restore wild-type adult survival only in adults lacking JH III, not in those lacking JHB3.”

Model organismslong-lived insulin-like receptor mutants lacking JH III; restoration of wild-type survival was not observed in mutants lacking JHB3

Distinct impacts of JH III and JHB₃ mediated by the insulin receptor upon Drosophila life span

Insect biochemistry and molecular biology·14 Jul 2026