Jujuboside a

1. Jujuboside a protects against oxidative stress and ROS signalling in worms.

   “Moreover, we found that JA also enhanced oxidative stress resistance in a manner dependent on the transcription factors DAF-16/FOXO3A and SKN-1/Nrf2.”

   Model organisms

   Jujuboside A extends healthspan and enhances resistance of oxidative stress in Caenorhabditis elegans via the transcription factor DAF-16/FOXO3A and SKN-1/Nrf2

   Frontiers in pharmacology·23 Jun 2026

More on Oxidative stress and ROS signalling

1. Jujuboside a decreases lipofuscin in worms.

   “JA increased the locomotion and decreased the aging pigment but did not affect the reproductive performance in C. elegans.”

   Model organisms

   Jujuboside A extends healthspan and enhances resistance of oxidative stress in Caenorhabditis elegans via the transcription factor DAF-16/FOXO3A and SKN-1/Nrf2

   Frontiers in pharmacology·23 Jun 2026

More on Lipofuscin

1. Jujuboside a improves locomotion in worms.

   “JA increased the locomotion and decreased the aging pigment but did not affect the reproductive performance in C. elegans.”

   Model organisms

   Jujuboside A extends healthspan and enhances resistance of oxidative stress in Caenorhabditis elegans via the transcription factor DAF-16/FOXO3A and SKN-1/Nrf2

   Frontiers in pharmacology·23 Jun 2026

1. Jujuboside a extends lifespan in worms.

   “JA extended the lifespan of Caenorhabditis elegans in dose-dependent manner.”

   Model organisms

   Jujuboside A extends healthspan and enhances resistance of oxidative stress in Caenorhabditis elegans via the transcription factor DAF-16/FOXO3A and SKN-1/Nrf2

   Frontiers in pharmacology·23 Jun 2026