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JM10101

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Innovative Research Team of High-level Local University in Shanghai and 3 more
  • Animals1

Outcomes

2

Aging symptoms

downin mice1

1 study

  1. JM10101 decreases aging symptoms in mice.

    “Both JM10001 and JM10101 mitigate aging symptoms in senescence-accelerated mice treated with doxorubicin and in naturally aged mice.”

    Animalsin doxorubicin-treated mice

    A Senomorphlytic Three-Drug Combination Discovered in Salsola collina for Delaying Aging Phenotypes and Extending Healthspan

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)29 Jul 2024

Lifespan

upin worms1

1 study

  1. JM10101 extends lifespan in worms.

    “JM10101 and comprising three chemical constituents of JM10001, preserves the original lifespan-extending activity in C. elegans.”

    Model organisms

    A Senomorphlytic Three-Drug Combination Discovered in Salsola collina for Delaying Aging Phenotypes and Extending Healthspan

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)29 Jul 2024

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