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INTERLEUKIN-34

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Agence Nationale de la Recherche and 7 more
  • Animals1

Outcomes

1

Insulin synthesis

upin mouse cells1

1 study

  1. INTERLEUKIN-34 increases insulin synthesis in mouse cells.

    “in the presence of pro-inflammatory cytokines, ex vivo murine islets of Langerhans exhibited a decreased insulin synthesis, which was restored in the presence of IL-34.”

    Cellsex vivo islets exposed to pro-inflammatory cytokinesislet of Langerhans

    IL-34 is expressed in the pancreas and regulates local inflammation

    Translational research : the journal of laboratory and clinical medicine22 Jul 2025

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