Hypoxia-mimetic compounds

Intervention

1 paper2 findings

  • 1 lab in 1 country
  • Funders: European Commission and 7 more
  • Animals1

Outcomes

2

Muscle strength

upin animals1

1 study
  1. Hypoxia-mimetic compounds improve muscle strength.

    “improves strength in chemotherapy-treated and aged mice”

    Animalsin chemotherapy-treated and aged mice

    Physiological hypoxia restrains the senescence-associated secretory phenotype via AMPK-mediated mTOR suppression

    Molecular cell5 Apr 2021

SASP

downin animals1

1 study
  1. Hypoxia-mimetic compounds decrease SASP.

    “treatment with hypoxia-mimetic compounds reduces SASP in cells and tissues”

    Animalsin chemotherapy-treated and aged mice

    Physiological hypoxia restrains the senescence-associated secretory phenotype via AMPK-mediated mTOR suppression

    Molecular cell5 Apr 2021

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