Hydroxycitric acid
Hydroxycitric acid has been studied in 2 papers since 2022: none in people yet, 2 in animals. The research so far is in animals. The newest paper, Apr 19, 2023: “The Ketogenic Diet but not Hydroxycitric Acid Keeps Brain Mitochondria Quality Control and mtDNA Integrity Under Focal Stroke”.
None of its findings points the other way.
- 1 lab in 1 country
- Funder: Russian Science Foundation
- Animals2
What did studies of Hydroxycitric acid find?
3Studies of Hydroxycitric acid measured 3 outcomes; the most studied are mitochondrial biogenesis (PGC-1α) (1 study), mortality (1) and stroke-induced injury (1).
Mitochondrial biogenesis (PGC-1α)
downin mice1
1 study
Mitochondrial biogenesis (PGC-1α)
downin mice1
Hydroxycitric acid inhibits mitochondrial biogenesis (PGC-1α) in mice.
“The hydroxycitric acid causes mortality and suppresses mitochondrial biogenesis in the liver.”
Animalsin miceliver
Molecular neurobiology
Mortality
upin mice1
1 study
Mortality
upin mice1
Hydroxycitric acid increases mortality in mice.
“The hydroxycitric acid causes mortality and suppresses mitochondrial biogenesis in the liver.”
Animalsin miceliver
Molecular neurobiology
Stroke-induced injury
upin mice1
1 study
Stroke-induced injury
upin mice1
Hydroxycitric acid increases stroke-induced injury in mice.
“The hydroxycitric acid, on the contrary, increased stroke-induced injury.”
Animalsin mice with focal strokebrain
Molecular neurobiology