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High-intensity progressive resistance and impact training

Intervention

1 paper4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: Australian Government and 2 more
  • Human trial1

Outcomes

4

Lumbar spine bone mineral density

upin humans1

1 study

  1. High-intensity progressive resistance and impact training increases lumbar spine bone mineral density in humans (4.1 ± 0.7% vs 2.0 ± 0.7%).

    “HiRIT improved LS BMD (4.1 ± 0.7%; 2.0 ± 0.7%, p = .039), stiffness index (1.6 ± 0.9%; -1.3 ± 0.9%, p = .025), and FTSTS (-10.7 ± 1.6%; -4.5 ± 1.7%, p = .010) compared with IAC.”

    Human trialosteopenia or osteoporosis / low BMDbonemalesn = 93

    A Comparison of Bone-Targeted Exercise Strategies to Reduce Fracture Risk in Middle-Aged and Older Men with Osteopenia and Osteoporosis: LIFTMOR-M Semi-Randomized Controlled Trial

    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research30 Mar 2020

More on Lumbar spine bone mineral density

Lean mass

upin humans1

1 study

  1. High-intensity progressive resistance and impact training increases lean mass in humans (1.5 ± 0.8% vs -2.4 ± 0.9%).

    “lean mass (1.5 ± 0.8%; -2.4 ± 0.9%, p = .002)”

    Human trialosteopenia or osteoporosis / low BMDmusclemalesn = 93

    A Comparison of Bone-Targeted Exercise Strategies to Reduce Fracture Risk in Middle-Aged and Older Men with Osteopenia and Osteoporosis: LIFTMOR-M Semi-Randomized Controlled Trial

    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research30 Mar 2020

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Physical function

upin humans1

1 study

  1. High-intensity progressive resistance and impact training improves physical function in humans (p < .05).

    “HiRIT improved trochanteric BMD (2.8 ± 0.8%; -0.1 ± 0.9%, p = .024), LS BMD (4.1 ± 0.7%; 0.9 ± 0.8%, p = .003), BUA (2.2 ± 0.7%; -0.8 ± 0.9%, p = .009), stiffness index (1.6 ± 0.9%; -2.0 ± 1.1%, p = .011), lean mass (1.5 ± 0.8%; -2.4 ± 0.9%, p = .002), TUG, FTSTS, BES, and LES (p < .05) compared with CON.”

    Human trialosteopenia or osteoporosis / low BMDmalesn = 93

    A Comparison of Bone-Targeted Exercise Strategies to Reduce Fracture Risk in Middle-Aged and Older Men with Osteopenia and Osteoporosis: LIFTMOR-M Semi-Randomized Controlled Trial

    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research30 Mar 2020

Bone mineral density

upin humans1

1 study

  1. High-intensity progressive resistance and impact training increases bone mineral density in humans (2.8 ± 0.8% vs -0.1 ± 0.9% (trochanteric), 4.1 ± 0.7% vs 0.9 ± 0.8% (LS)).

    “HiRIT improved trochanteric BMD (2.8 ± 0.8%; -0.1 ± 0.9%, p = .024), LS BMD (4.1 ± 0.7%; 0.9 ± 0.8%, p = .003)”

    Human trialosteopenia or osteoporosis / low BMDbonemalesn = 93

    A Comparison of Bone-Targeted Exercise Strategies to Reduce Fracture Risk in Middle-Aged and Older Men with Osteopenia and Osteoporosis: LIFTMOR-M Semi-Randomized Controlled Trial

    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research30 Mar 2020

More on Bone mineral density

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