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High-fat and high-sugar diet

Exposure

2 papers3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Humans1

Outcomes

1

Hippocampus-dependent recognition memory

downin humans1

1 study

  1. High-fat and high-sugar diet impairs hippocampus-dependent recognition memory in humans.

    “higher HFS consumption was associated with worse hippocampus-dependent recognition memory and executive function, only in participants with age below 65”

    Humans

    DIET AND COGNITION IN AGING: EFFECTS OF HIGH-FAT-SUGAR DIETS ON MEMORY AND EXECUTIVE FUNCTIONING

    GSA 2024 abstractDec 31, 2024

Associations

2

Memory performance

downin humans1

1 study

  1. High-fat and high-sugar diet predicts memory performance in humans.

    “higher HFS predicted lower memory performance only in participants with no multi-morbidity.”

    Humansin participants with no multi-morbidity

    DIET AND COGNITION IN AGING: EFFECTS OF HIGH-FAT-SUGAR DIETS ON MEMORY AND EXECUTIVE FUNCTIONING

    GSA 2024 abstractDec 31, 2024

Subjective memory complaints

upin humans1

1 study

  1. High-fat and high-sugar diet is associated with subjective memory complaints in humans.

    “higher HFS consumption was strongly associated with more subjective memory complaints in older adults after controlling for potential covariates.”

    Humansafter controlling for potential covariates

    DIET AND COGNITION IN AGING: EFFECTS OF HIGH-FAT-SUGAR DIETS ON MEMORY AND EXECUTIVE FUNCTIONING

    GSA 2024 abstractDec 31, 2024

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