Heavy water
Across all fields, 1 paper: none in people yet, 1 in cells
- 1 lab in 1 country
- Funders: California Institute for Regenerative Medicine and 2 more
- Cells1
Outcomes
3Metabolic consumption and disposal
downin yeast cells1
1 study
Metabolic consumption and disposal
downin yeast cells1
Heavy water decreases metabolic consumption and disposal in yeast cells.
“Heavy water substantially suppresses endogenous generation of reactive oxygen species (ROS) and slows the pace of metabolic consumption and disposal.”
Cells
Yeast longevity promoted by reversing aging-associated decline in heavy isotope content
NPJ aging and mechanisms of disease
Reactive oxygen species generation
downin yeast cells1
1 study
Reactive oxygen species generation
downin yeast cells1
Heavy water decreases reactive oxygen species generation in yeast cells.
“Heavy water substantially suppresses endogenous generation of reactive oxygen species (ROS)”
Cells
Yeast longevity promoted by reversing aging-associated decline in heavy isotope content
NPJ aging and mechanisms of disease
Chronological lifespan
upin yeast cells1+85% chronological lifespan
1 study
Chronological lifespan
upin yeast cells1+85% chronological lifespan
Heavy water extends chronological lifespan in yeast cells (up to 85% longer chronological lifespan).
“Supplementation of deuterium, a heavy hydrogen isotope, through heavy water (D2O) uptake extends yeast chronological lifespan (CLS) by up to 85%”
Cells
Yeast longevity promoted by reversing aging-associated decline in heavy isotope content
NPJ aging and mechanisms of disease
Funding
1 grant since 2020National Institute of General Medical SciencesUS$1.4m