GSK126
- 1 lab in 1 country
- Funders: National Natural Science Foundation of China and 2 more
- Animals1
Outcomes
2Cellular senescence
downin mice1−54%
1 study
Cellular senescence
downin mice1−54%
GSK126 decreases cellular senescence in mice (~54%).
“Pharmacological inhibition of EZH2 by GSK126 alleviated kidney aging and podocyte injury markers by approximately 54% in db/db mice.”
Animalsin db/db mice
Cellular and molecular life sciences : CMLS11 Mar 2026
Podocyte injury
downin mice1−54%
1 study
Podocyte injury
downin mice1−54%
GSK126 decreases podocyte injury in mice (~54%).
“Pharmacological inhibition of EZH2 by GSK126 alleviated kidney aging and podocyte injury markers by approximately 54% in db/db mice.”
Animalsin db/db mice
Cellular and molecular life sciences : CMLS11 Mar 2026
Latest
1 in 12 monthsCellular and Molecular Life Sciences
Histone methyltransferase EZH2 drives podocyte injury and senescence in diabetic nephropathy through STAT3 activation
Experiments in miceCellular senescence