GLP-1-based pharmacotherapies

Intervention

1 paper2 findings

Outcomes

1

Fat mass and fat-free or lean mass

downin humans1

1 study
  1. GLP-1-based pharmacotherapies decrease fat mass and fat-free or lean mass in humans.

    “Clinical studies reported greater reductions in fat mass than in fat-free or lean mass, neither of which represents skeletal muscle exclusively.”

    Reviewclinical studies reviewed

    GLP-1-Based Pharmacotherapies and Skeletal Muscle Health in Obesity: A Narrative Review of Body Composition, Muscle Function, and Sarcopenia-Related Outcomes

    Nutrients1 Oct 2026

Associations

1

Muscle quantity and function

mixedin humans1

1 study
  1. GLP-1-based pharmacotherapies are associated with muscle quantity and function in humans.

    “Direct muscle and functional outcomes were assessed in few studies and yielded mixed results.”

    Reviewclinical studies reviewedskeletal muscle

    GLP-1-Based Pharmacotherapies and Skeletal Muscle Health in Obesity: A Narrative Review of Body Composition, Muscle Function, and Sarcopenia-Related Outcomes

    Nutrients1 Oct 2026

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