GFAP-Npc1

1 paper1 finding

1 lab in 1 country

Animals1

Outcomes

1

Lifespan

upin mice1

1 study

GFAP-Npc1 extends lifespan in mice (up to 600 days).
“further extended the lifespan of Npc1nmf164 homozygotes on a BALB/cJ background (up to 600days).”
Animalson BALB/cJ background
In Niemann-Pick C1 mouse models, glial-only expression of the normal gene extends survival much further than do changes in genetic background or treatment with hydroxypropyl-beta-cyclodextrin
Gene6 Dec 2017

Latest

Gene6 Dec

In Niemann-Pick C1 mouse models, glial-only expression of the normal gene extends survival much further than do changes in genetic background or treatment with hydroxypropyl-beta-cyclodextrin

Experiments in miceInterventions