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Gamma delta t cells

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Buck Institute for Research on Aging and 1 more
  • Animals1

Outcomes

2

Idiopathic pulmonary fibrosis

downin mice1

1 study

  1. Gamma delta t cells decrease idiopathic pulmonary fibrosis in mice.

    “adoptive cell transfer of γδ T cells into an IPF mouse model reduces the number of p21-expressing senescent cells in affected lung tissue and improves outcomes.”

    Animalsadoptive cell transferlung

    γδ T Cells Target and Ablate Senescent Cells in Aging and Alleviate Pulmonary Fibrosis

    bioRxiv (Cold Spring Harbor Laboratory)9 May 2025Preprint

More on Idiopathic pulmonary fibrosis

Cellular senescence

downin mice1

1 study

  1. Gamma delta t cells decrease cellular senescence in mice.

    “adoptive cell transfer of γδ T cells into an IPF mouse model reduces the number of p21-expressing senescent cells in affected lung tissue and improves outcomes.”

    Animalsadoptive cell transferlung

    γδ T Cells Target and Ablate Senescent Cells in Aging and Alleviate Pulmonary Fibrosis

    bioRxiv (Cold Spring Harbor Laboratory)9 May 2025Preprint

More on Cellular senescence

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