Gal-dmor-gem
1 paper2 findings
- 1 lab in 1 country
- Funder: National Natural Science Foundation of China
- Animals1
Outcomes
2Senescence-associated beta-galactosidase
downin mice1
1 study
Senescence-associated beta-galactosidase
downin mice1
Gal-dmor-gem decreases senescence-associated beta-galactosidase in mice.
“reducing SA-β-gal, IL-6, and lamin B1 abnormalities in multiple organs”
Animalsin senescent mice0.5 mg/kg
Journal of medicinal chemistry24 Mar 2026
Body weight
upin mice1
1 study
Body weight
upin mice1
Gal-dmor-gem improves body weight in mice.
“In senescent mice, Gal-dMor-Gem (0.5 mg/kg) surpassed SSK1 in restoring body weight, improving biochemical parameters, and reducing SA-β-gal, IL-6, and lamin B1 abnormalities in multiple organs.”
Animalsin senescent mice0.5 mg/kg
Journal of medicinal chemistry24 Mar 2026
Latest
1 in 12 monthsJournal of Medicinal Chemistry
Design and Optimization of Lysosome-Targeted β-Galactoside Senolytic Prodrugs: Harnessing the Aromatic Ring of Self-Immolative Linkers
Experiments in miceInterventions