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G9A inhibitor

Intervention

1 paper studies it1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: China Postdoctoral Science Foundation and 5 more
  • Model organisms1

Outcomes

1

Lifespan

upin worms1

1 study

  1. G9A inhibitor extends lifespan in worms.

    “treating daf-2 animals with the H3K9me1/2 methyltransferase G9a inhibitor also extends lifespan and increases stress resistance”

    Model organismsin daf-2 mutants

    H3K9me1/2 methylation limits the lifespan of daf-2 mutants in C. elegans

    eLifeSep 20, 2022

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