Forced exercise

Intervention

2 papers3 findings

  • 1 lab in 1 country
  • Funder: Johns Hopkins Bloomberg School of Public Health
  • Animals2

Outcomes

3

Alpha motor neuron count

upin mice1

1 study
  1. Forced exercise increases alpha motor neuron count in mice.

    “Alpha motor neuron counts were highest in mice with wheels and in mice exposed to forced exercise regime in both mouse strains.”

    Animalsmales

    Effects of environmental enrichment on the amyotrophic lateral sclerosis mouse model

    Laboratory animals26 Feb 2009

More on Alpha motor neuron count

Stride length

upin mice1

1 study
  1. Forced exercise improves stride length in mice.

    “In SOD1 mice, stride length remained longest throughout the progression of the disease in mice exposed to the forced exercise regime compared with other SOD1 conditions.”

    Animalsin SOD1-G93A micemales

    Effects of environmental enrichment on the amyotrophic lateral sclerosis mouse model

    Laboratory animals26 Feb 2009

Lifespan

upin mice1

1 study
  1. Forced exercise extends lifespan in mice.

    “The SOD1 mice exposed to the forced exercise regime and wheel access did better in average lifespan and Rotor-Rod performance, than SOD1 mice exposed to the standard cage and mouse house conditions.”

    Animalsin SOD1-G93A micemales

    Effects of environmental enrichment on the amyotrophic lateral sclerosis mouse model

    Laboratory animals26 Feb 2009

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