Fasting plasma glucose

Fasting plasma glucose has been studied in 2 papers since 2025: 2 observational studies in people; 2 in the past year. The newest paper, Jul 3, 2026: “Unhealthy fat distribution as a sex-specific predictor of declining hippocampus insulin sensitivity”.

Exposure

2 papers study it2 findingsUpdated

See all 2 papers on fasting plasma glucose

At a glance

The findings reach people, from one lab or study. 2 independent labs in 2 countries.

“Hazard ratios (HRs) of incident CRMM associated with each 1-standard deviation (SD) increase in FPG, 2hPG, insulin (natural log), and HOMA-IR (natural log) were 1.48 (95 % CI: 1.34-1.64)”
Nonlinear association between glycemic markers and incident cardio‑renal‑metabolic multimorbidity: two decades of follow‑up in the Tehran Lipid and Glucose StudyAmerican journal of preventive cardiology2025doi:10.1016/j.ajpc.2025.101353

None of its findings points the other way.

Humans: a single group. Cells, worms or flies and mice: nothing yet.
  • 2 independent labs in 2 countries
  • Funders: Bundesministerium für Forschung, Technologie und Raumfahrt and 5 more
  • Humans2

What is fasting plasma glucose linked with?

2

Studies link fasting plasma glucose with 2 measures: hippocampal insulin response and cardio-renal-metabolic multimorbidity.

Hippocampal insulin response

downin humans1

1 study
  1. Fasting plasma glucose predicts hippocampal insulin response in humans (independently of sex, with increasing age) (estimate 0.533, p=0.016).

    “Fasting plasma glucose levels predicted lower hippocampal insulin response with age independently of sex (estimate 0.533, p=0.016).”

    Humansindependently of sex, with increasing agehippocampus

    Unhealthy fat distribution as a sex-specific predictor of declining hippocampus insulin sensitivity

    Diabetologia

More on Hippocampal insulin response

Cardio-renal-metabolic multimorbidity

upin humans1HR 1.48

1 study
  1. Fasting plasma glucose is linked with a higher risk of cardio-renal-metabolic multimorbidity in humans (per 1-standard deviation increase) (HR 1.48 (95% CI 1.34-1.64) per 1-SD increase).

    “Hazard ratios (HRs) of incident CRMM associated with each 1-standard deviation (SD) increase in FPG, 2hPG, insulin (natural log), and HOMA-IR (natural log) were 1.48 (95 % CI: 1.34-1.64)”

    Humansper 1-standard deviation increasemedian follow-up of 15.3 years

    Nonlinear association between glycemic markers and incident cardio‑renal‑metabolic multimorbidity: two decades of follow‑up in the Tehran Lipid and Glucose Study

    American journal of preventive cardiology

More on Cardio-renal-metabolic multimorbidity

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 1Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 01 paper in 12 months