AgingResearch.NewsJoin free

Extracellular vesicles from HIV-positive individuals

Intervention

1 paper studies it2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Heart, Lung, and Blood Institute and 4 more
  • Humans1

Outcomes

2

Cellular senescence

upin mice1

1 study

  1. Extracellular vesicles from HIV-positive individuals induce cellular senescence in mice.

    “increased atherosclerosis in apoE-/- mice, which was accompanied by elevated senescence and impaired functionality of arterial cells and lin− BMCs.”

    Animalsin apoE-/- mice

    HIV Promotes Atherosclerosis via Circulating Extracellular Vesicle MicroRNAs

    International journal of molecular sciencesApr 20, 2023

More on Cellular senescence

Atherosclerosis

upin mice1

1 study

  1. Extracellular vesicles from HIV-positive individuals increase atherosclerosis in mice.

    “HIVposEVs, but not HIV PLdepEVs or HIVnegEVs (EVs from HIVneg individuals), increased atherosclerosis in apoE-/- mice”

    Animalsin apoE-/- mice

    HIV Promotes Atherosclerosis via Circulating Extracellular Vesicle MicroRNAs

    International journal of molecular sciencesApr 20, 2023

More on Atherosclerosis

Latest

Related