Exercise therapy
Exercise therapy has been studied in 8 papers since 2017: 2 trials and 1 observational study in people, 4 reviews; 3 in the past year. The newest paper, Oct 15, 2026: “Effectiveness of comprehensive treatment of age-associated spinal diseases (original study)”.
1 new paper in 30 daysSee all 8
“Nonfrail clients who participated in exercise therapy were more likely to become prefrail (OR 1.05).”
None of its findings points the other way.
- 2 independent labs in 1 country
- Funders: Department of Anesthesiology and Pain Medicine, Faculty of Medicine, University of Ottawa and 8 more
- Human trial2
- Humans1
What did studies of Exercise therapy find?
2Studies of Exercise therapy measured 2 outcomes; the most studied are physical inactivity syndrome (1 study) and depression (1).
Physical inactivity syndrome
downin humans1
1 study
Physical inactivity syndrome
downin humans1
Exercise therapy prevents physical inactivity syndrome in humans.
“the effects of rehabilitation and exercise therapy required to prevent and treat PIS are introduced.”
Reviewto prevent and treat PIS
Physical Inactivity Syndrome: A Risk Factor and Target for Intervention-A Narrative Review
Progress in rehabilitation medicine
Depression
downin humans1
1 study
Depression
downin humans1
Exercise therapy protects against depression in humans.
“Physical activity and exercise therapy have been identified as a promising method for preventing and treating depression in the elderly.”
Reviewfrail elderly people
Medicine
What is Exercise therapy linked with?
4Studies link Exercise therapy with 4 measures, most often transition to nonfrail status (1 study), transition to prefrail status (1) and quality of life (1).
Transition to nonfrail status
upin humans1OR 1.26
1 study
Transition to nonfrail status
upin humans1OR 1.26
Exercise therapy is associated with transition to nonfrail status in humans (OR 1.26).
“Prefrail clients who participated in exercise therapy were more likely to become nonfrail (OR 1.26).”
HumansPrefrail home care clients
Journal of the American Medical Directors Association
Transition to prefrail status
upin humans1OR 1.05
1 study
Transition to prefrail status
upin humans1OR 1.05
Exercise therapy is associated with transition to prefrail status in humans (OR 1.05).
“Nonfrail clients who participated in exercise therapy were more likely to become prefrail (OR 1.05).”
HumansNonfrail home care clients
Journal of the American Medical Directors Association
Quality of life
upin humans1
1 study
Quality of life
upin humans1
Exercise therapy is associated with quality of life in humans.
“Exercise therapy, applied pre-, or post-operatively, was associated with significant improvements in functional outcomes and improved quality of life.”
Reviewfrail surgical patients; applied pre- or postoperatively
Interventions to improve the outcomes of frail people having surgery: A systematic review
PloS one
Functional outcomes
upin humans1
1 study
Functional outcomes
upin humans1
Exercise therapy is associated with functional outcomes in humans.
“Exercise therapy, applied pre-, or post-operatively, was associated with significant improvements in functional outcomes and improved quality of life.”
Reviewfrail surgical patients; applied pre- or postoperatively
Interventions to improve the outcomes of frail people having surgery: A systematic review
PloS one
Funding
11 grants since 2018Japan Society for the Promotion of ScienceJP¥19.2mNational Heart, Lung, and Blood InstituteUS$3.8mNational Institute of General Medical SciencesUS$1m
Japan Society for the Promotion of ScienceTokyo Women's Medical UniversityJP¥4.7m2026–2030
Elucidation of the roles of exercise therapy, SIRT1, and myokines in uremic sarcopenia
Japan Society for the Promotion of ScienceJuntendo UniversityJP¥4.6m2026–2029
Development of a novel exercise therapy using exercise and PACAP aimed at improving sarcopenia
Japan Society for the Promotion of ScienceKurume UniversityJP¥4.3m2026–2029
Japan Society for the Promotion of ScienceNippon Dental UniversityJP¥4.3m2025–2029
Japan Society for the Promotion of ScienceUniversity of TokyoJP¥1.4m2025–2027
Preoperative exercise therapy for surgery triggered inflammation
National Institute of General Medical SciencesFeinstein Institutes for Medical ResearchUS$360.1k2022–2025
HL-132: Increasing Adherence to Guideline-Based Exercise Therapy For Chronic Heart Failure
National Heart, Lung, and Blood InstituteUniversity of California, San DiegoUS$752.4k2018–2023
National Institute on AgingUniversity of FloridaUS$233k2019–2023
UKRI | Medical Research CouncilUniversity of Leeds£655.3k2019–2022
National Institute of Nursing ResearchUniversity of MinnesotaUS$7.3k2017–2019