Exercise therapy

Exercise therapy has been studied in 8 papers since 2017: 2 trials and 1 observational study in people, 4 reviews; 3 in the past year. The newest paper, Oct 15, 2026: “Effectiveness of comprehensive treatment of age-associated spinal diseases (original study)”.

Intervention

8 papers study it6 findingsUpdated

MeSH

1 new paper in 30 daysSee all 8

“Nonfrail clients who participated in exercise therapy were more likely to become prefrail (OR 1.05).”
Frailty Index Status of Canadian Home Care Clients Improves With Exercise Therapy and Declines in the Presence of PolypharmacyJournal of the American Medical Directors Association2020doi:10.1016/j.jamda.2020.01.004

None of its findings points the other way.

  • 2 independent labs in 1 country
  • Funders: Department of Anesthesiology and Pain Medicine, Faculty of Medicine, University of Ottawa and 8 more
  • Human trial2
  • Humans1

What did studies of Exercise therapy find?

2

Studies of Exercise therapy measured 2 outcomes; the most studied are physical inactivity syndrome (1 study) and depression (1).

Physical inactivity syndrome

downin humans1

1 study
  1. Exercise therapy prevents physical inactivity syndrome in humans.

    “the effects of rehabilitation and exercise therapy required to prevent and treat PIS are introduced.”

    Reviewto prevent and treat PIS

    Physical Inactivity Syndrome: A Risk Factor and Target for Intervention-A Narrative Review

    Progress in rehabilitation medicine

More on Physical inactivity syndrome

Depression

downin humans1

1 study
  1. Exercise therapy protects against depression in humans.

    “Physical activity and exercise therapy have been identified as a promising method for preventing and treating depression in the elderly.”

    Reviewfrail elderly people

    The effects of physical activity and exercise therapy on frail elderly depression: A narrative review

    Medicine

More on Depression

What is Exercise therapy linked with?

4

Studies link Exercise therapy with 4 measures, most often transition to nonfrail status (1 study), transition to prefrail status (1) and quality of life (1).

Transition to nonfrail status

upin humans1OR 1.26

1 study
  1. Exercise therapy is associated with transition to nonfrail status in humans (OR 1.26).

    “Prefrail clients who participated in exercise therapy were more likely to become nonfrail (OR 1.26).”

    HumansPrefrail home care clients

    Frailty Index Status of Canadian Home Care Clients Improves With Exercise Therapy and Declines in the Presence of Polypharmacy

    Journal of the American Medical Directors Association

Transition to prefrail status

upin humans1OR 1.05

1 study
  1. Exercise therapy is associated with transition to prefrail status in humans (OR 1.05).

    “Nonfrail clients who participated in exercise therapy were more likely to become prefrail (OR 1.05).”

    HumansNonfrail home care clients

    Frailty Index Status of Canadian Home Care Clients Improves With Exercise Therapy and Declines in the Presence of Polypharmacy

    Journal of the American Medical Directors Association

Quality of life

upin humans1

1 study
  1. Exercise therapy is associated with quality of life in humans.

    “Exercise therapy, applied pre-, or post-operatively, was associated with significant improvements in functional outcomes and improved quality of life.”

    Reviewfrail surgical patients; applied pre- or postoperatively

    Interventions to improve the outcomes of frail people having surgery: A systematic review

    PloS one

Functional outcomes

upin humans1

1 study
  1. Exercise therapy is associated with functional outcomes in humans.

    “Exercise therapy, applied pre-, or post-operatively, was associated with significant improvements in functional outcomes and improved quality of life.”

    Reviewfrail surgical patients; applied pre- or postoperatively

    Interventions to improve the outcomes of frail people having surgery: A systematic review

    PloS one

Funding

11 grants since 2018

Japan Society for the Promotion of ScienceJP¥19.2mNational Heart, Lung, and Blood InstituteUS$3.8mNational Institute of General Medical SciencesUS$1m

Latest

Nov 2025: 0Dec 2025: 1Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 1Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 13 papers in 12 months