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Ethyl caffeate

Intervention

1 paper3 findings

PubChemChEBIMeSH

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Japan Society for the Promotion of Science and 1 more
  • Model organisms1

Outcomes

3

Rough-eye phenotype

downin flies1

1 study

  1. Ethyl caffeate decreases rough-eye phenotype in flies.

    “feeding of EC was able to partially rescue the rough eye phenotype”

    Model organismsin Drosophila expressing human Aβ42eye

    Ethyl caffeate ameliorated amyloid-beta42 protein-associated toxicity in PC12 cells and Drosophila melanogaster

    Geriatrics & gerontology international26 Oct 2021

Mobility

upin flies1

1 study

  1. Ethyl caffeate improves mobility in flies.

    “enhanced the mobility of middle-aged AD Drosophila.”

    Model organismsin AD Drosophila expressing human Aβ42

    Ethyl caffeate ameliorated amyloid-beta42 protein-associated toxicity in PC12 cells and Drosophila melanogaster

    Geriatrics & gerontology international26 Oct 2021

Lifespan

upin flies1

1 study

  1. Ethyl caffeate extends lifespan in flies.

    “feeding of EC was able to partially rescue the rough eye phenotype, lengthen the lifespan of AD Drosophila”

    Model organismsin Drosophila expressing human Aβ42

    Ethyl caffeate ameliorated amyloid-beta42 protein-associated toxicity in PC12 cells and Drosophila melanogaster

    Geriatrics & gerontology international26 Oct 2021

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