Estren

1. Estren decreases cell death in mice.

   “Notably, estren was more effective in reducing BFC cell death in aged mice following injection of Aβ1–42.”

   AnimalsAβ1–42 injection into basal forebrainbasal forebrainfemales

   Estren prevents beta-amyloid-induced basal forebrain cholinergic loss and long-term spatial memory deficits in aged female mice

   Scientific reports·27 Apr 2026

1. Estren prevents long-term spatial memory deficit in mice.

   “estren prevented the Aβ1–42-induced loss of BFC neurons and the long-term spatial memory deficit following injection into the mouse basal forebrain of aged female mice.”

   AnimalsAβ1–42 injection into basal forebrainfemales

   Estren prevents beta-amyloid-induced basal forebrain cholinergic loss and long-term spatial memory deficits in aged female mice

   Scientific reports·27 Apr 2026

1. Estren prevents BFC neurons in mice.

   “estren prevented the Aβ1–42-induced loss of BFC neurons and the long-term spatial memory deficit following injection into the mouse basal forebrain of aged female mice.”

   AnimalsAβ1–42-induced basal forebrain toxicitybasal forebrainfemales

   Estren prevents beta-amyloid-induced basal forebrain cholinergic loss and long-term spatial memory deficits in aged female mice

   Scientific reports·27 Apr 2026

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