Estradiol valerate + testosterone undecanoate

Estradiol valerate + testosterone undecanoate has been studied in 2 papers since 2012: 2 trials in people. The newest paper, Oct 25, 2012: “Effect of estrogen and testosterone replacement therapy on cognitive fatigue”.

Intervention

2 papers study it2 findingsUpdated

“Treatment-dependent and hormone-specific effects on serum metabolites were observed, ranging between 69% reduction and 184% increase”
Effects of oestrogen and testosterone therapy on serum metabolites in postmenopausal womenClinical endocrinology2012doi:10.1111/j.1365-2265.2012.04374.x
  • 1 lab in 1 country
  • Human trial2

What did studies of Estradiol valerate + testosterone undecanoate find?

1

Studies of Estradiol valerate + testosterone undecanoate measured 1 outcome; the most studied are cognitive fatigue (1 study).

Cognitive fatigue

no changein humans1

1 study
  1. Estradiol valerate + testosterone undecanoate has no effect on cognitive fatigue in humans.

    “Treatment with testosterone + estrogen had no significant effect on cognitive fatigue”

    Human trialsurgically induced menopauseestradiol valerate in combination with testosterone undecanoate24 weeksfemalesn = 50

    Effect of estrogen and testosterone replacement therapy on cognitive fatigue

    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology

What is Estradiol valerate + testosterone undecanoate linked with?

1

Studies link Estradiol valerate + testosterone undecanoate with 1 measure, most often serum metabolites (1 study).

Serum metabolites

mixedin humans1

1 study
  1. Estradiol valerate + testosterone undecanoate is associated with serum metabolites in humans (ranging between 69% reduction and 184% increase).

    “Treatment-dependent and hormone-specific effects on serum metabolites were observed, ranging between 69% reduction and 184% increase”

    Human trialserum3 monthsfemalesn = 60

    Effects of oestrogen and testosterone therapy on serum metabolites in postmenopausal women

    Clinical endocrinology

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