Esrra inhibitors

1 paper1 finding

1 lab in 1 country

Funders: Basic and Applied Basic Research Foundation of Guangdong Province and 2 more

Animals1

Outcomes

1

Osteoarthritis progression

downin mice1

1 study

Esrra inhibitors decrease osteoarthritis progression in mice.
“Adipocyte-specific ablation or pharmacological inhibition of ESRRA reduces CFD levels particularly in adipocyte-rich bone marrow, attenuating osteoarthritis progression in aged mice.”
Animals
Targeting adipocyte ESRRA alleviates osteoarthritis via interrupting inter-organelle crosstalk of complement C3-CFD-MAC cascade
Bone research29 Apr 2026

Latest

1 in 12 months

Bone Research30 Apr

Targeting adipocyte ESRRA alleviates osteoarthritis via interrupting inter-organelle crosstalk of complement C3-CFD-MAC cascade

Experiments in miceComplement system