Environmental noise exposure
3 papers4 findings
- 2 independent labs in 1 country
- Funder: Department for Environment, Food and Rural Affairs, UK Government
- Humans3
Outcomes
2GWR
upin humans1
1 study
GWR
upin humans1
Environmental noise exposure increases GWR in humans (20.11 ± 0.93 vs 19.68 ± 0.96, p = 0.036).
“The whole‐brain GWR was significantly higher in the high noise exposure group (20.11 ± 0.93) compared to that in the low noise exposure group (19.68 ± 0.96, p = 0.036).”
Humanshigh-noise vs low-noise exposure groupsbrainn = 106
Environmental noise exposure and a new biomarker of neurodegeneration in Alzheimer's disease
AAIC 2025 abstract23 Dec 2025
Cortical gray to white matter signal intensity ratio
upin humans1
1 study
Cortical gray to white matter signal intensity ratio
upin humans1
Environmental noise exposure increases cortical gray to white matter signal intensity ratio in humans (20.11 ± 0.93 vs 19.68 ± 0.96, p = 0.036).
“The whole‐brain GWR was significantly higher in the high noise exposure group (20.11 ± 0.93) compared to that in the low noise exposure group (19.68 ± 0.96, p = 0.036).”
Humansn = 106
Environmental noise exposure and a new biomarker of neurodegeneration in Alzheimer's disease
AAIC 2025 abstract23 Dec 2025
More on Cortical gray to white matter signal intensity ratio
Associations
2Brain age gap
upin humans1
1 study
Brain age gap
upin humans1
Environmental noise exposure is associated with brain age gap in humans (-8.1 versus -12.1 years; p = 0.0036).
“High environmental noise exposure was associated with a less negative BAG in the TSAN model than low environmental noise exposure”
HumansHigh versus low residential environmental noise exposure; TSAN modelbrainDaytime noise ≥60 dB or nighttime noise ≥55 dBn = 108
Neurotoxicology and teratology16 Oct 2026
Cortical gray to white matter signal intensity ratio
upin humans1
1 study
Cortical gray to white matter signal intensity ratio
upin humans1
Environmental noise exposure is associated with cortical gray to white matter signal intensity ratio in humans (r = 0.203, p = 0.037).
“Whole‐brain GWR values were significantly correlated with night noise levels ( r = 0.203, p = 0.037).”
Humansn = 106
Environmental noise exposure and a new biomarker of neurodegeneration in Alzheimer's disease
AAIC 2025 abstract23 Dec 2025
More on Cortical gray to white matter signal intensity ratio
Funding
1 grant since 2019Department for Environment, Food and Rural Affairs, UK Government£10k