Engineered exosomes delivering LAMP2A

Intervention

1 paper2 findings

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Animals1

Outcomes

2

Cellular senescence

downin animals1

1 study
  1. Engineered exosomes delivering LAMP2A decreases cellular senescence.

    “effectively delaying cellular senescence and significantly attenuating IVDD progression.”

    Animalsin an in vivo model

    Acetylation Regulates ACSL4 Degradation Through Chaperone-Mediated Autophagy to Alleviate Intervertebral Disc Degeneration

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)21 Nov 2025

More on Cellular senescence

Intervertebral disc degeneration

downin animals1

1 study
  1. Engineered exosomes delivering LAMP2A decreases intervertebral disc degeneration.

    “engineered exosomes are harnessed to deliver the key CMA receptor LAMP2A in an in vivo model, effectively delaying cellular senescence and significantly attenuating IVDD progression.”

    Animalsin an in vivo model

    Acetylation Regulates ACSL4 Degradation Through Chaperone-Mediated Autophagy to Alleviate Intervertebral Disc Degeneration

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)21 Nov 2025

More on Intervertebral disc degeneration

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