Early time-restricted eating
2 papers9 findings
- 1 lab in 1 country
- Funders: National Heart, Lung, and Blood Institute and 1 more
- Human trial2
Outcomes
9Metabolic regulation
upin humans1
1 study
Metabolic regulation
upin humans1
Early time-restricted eating improves metabolic regulation in humans.
“along with improvements in BMI, fasting glucose, and lipid profiles (All p < 0.05)”
Human trial1-monthmalesn = 23
Frontiers in aging18 Feb 2026
Immediate recall
upin humans1
1 study
Immediate recall
upin humans1
Early time-restricted eating improves immediate recall in humans.
“delayed recall and immediate recall scores demonstrated a significant increase (All p < 0.05)”
Human trial1-monthmalesn = 23
Frontiers in aging18 Feb 2026
Delayed recall
upin humans1
1 study
Delayed recall
upin humans1
Early time-restricted eating improves delayed recall in humans.
“delayed recall and immediate recall scores demonstrated a significant increase (All p < 0.05)”
Human trial1-monthmalesn = 23
Frontiers in aging18 Feb 2026
Brain age gap
downin humans1
1 study
Brain age gap
downin humans1
Early time-restricted eating decreases brain age gap in humans.
“males with MetS showed a significant reduction in BAG difference (p < 0.05)”
Human trial1-monthmalesn = 23
Frontiers in aging18 Feb 2026
Body fat and trunk fat
downin humans1
1 study
Body fat and trunk fat
downin humans1
Early time-restricted eating decreases body fat and trunk fat in humans.
“In a secondary analysis of 59 completers, eTRE+ER was also more effective for losing body fat and trunk fat than CON+ER.”
Human trialSecondary analysis of completers with obesity; both groups received energy restriction8-hour eating window from 7:00 to 15:0014 weeksn = 59
JAMA internal medicine1 Sep 2022
Mood disturbances
downin humans1
1 study
Mood disturbances
downin humans1
Early time-restricted eating decreases mood disturbances in humans.
“eTRE was more effective for losing weight and improving diastolic blood pressure and mood than eating over a window of 12 or more hours”
Human trialAdults with obesity receiving energy restriction; comparison with ≥12-hour eating window8-hour eating window from 7:00 to 15:0014 weeksn = 90
JAMA internal medicine1 Sep 2022
Diastolic blood pressure
downin humans1
1 study
Diastolic blood pressure
downin humans1
Early time-restricted eating decreases diastolic blood pressure in humans (-4 mm Hg; 95% CI -8 to 0 mm Hg; P = .04).
“The eTRE+ER intervention also improved diastolic blood pressure (-4 mm Hg; 95% CI, -8 to 0 mm Hg; P = .04)”
Human trialAdults with obesity; both groups received energy restriction; comparator eating window ≥12 hours8-hour eating window from 7:00 to 15:0014 weeksn = 90
JAMA internal medicine1 Sep 2022
Body fat
no changein humans1
1 study
Body fat
no changein humans1
Early time-restricted eating has no effect on body fat in humans (-1.4 kg versus control; 95% CI -2.9 to 0.2 kg).
“but did not affect body fat (-1.4 kg; 95% CI, -2.9 to 0.2 kg; P = .09)”
Human trialAdults with obesity; both groups received energy restriction; primary analysis versus ≥12-hour eating window8-hour eating window from 7:00 to 15:0014 weeksn = 90
JAMA internal medicine1 Sep 2022
Body weight
downin humans1
1 study
Body weight
downin humans1
Early time-restricted eating decreases body weight in humans (-2.3 kg versus control; 95% CI -3.7 to -0.9 kg).
“The eTRE+ER intervention was more effective for losing weight (-2.3 kg; 95% CI, -3.7 to -0.9 kg; P = .002)”
Human trialAdults with obesity; both groups received energy restriction; comparator eating window ≥12 hours8-hour eating window from 7:00 to 15:0014 weeks72 (80%) femalesn = 90
JAMA internal medicine1 Sep 2022