Dynamic compressive loading

Intervention1 paper3 findings

C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper that declares the maker’s interest.

1 lab in 1 country

Funders: Boston University and 2 more

  • Cells1

Outcomes

3

Mechanotransduction

downin mice1

1 study
  1. Dynamic compressive loading impairs mechanotransduction in mice.

    Animalsin aged tendonsflexor tendon

    Aged tendons have impaired mechanosensitivity and lower thresholds for injury under dynamic compression · Journal of biomechanics · 18 Aug 2026

Mechanotransduction →

Collagen

upin mice1

1 study
  1. Dynamic compressive loading increases collagen in mice.

    Animalshigh compression in young tendonsflexor tendon

    Aged tendons have impaired mechanosensitivity and lower thresholds for injury under dynamic compression · Journal of biomechanics · 18 Aug 2026

Collagen →

Glycosaminoglycan

upin mice1

1 study
  1. Dynamic compressive loading increases glycosaminoglycan in mice.

    Animalshigh compression in young tendonsflexor tendon

    Aged tendons have impaired mechanosensitivity and lower thresholds for injury under dynamic compression · Journal of biomechanics · 18 Aug 2026

Glycosaminoglycan →

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