Desmosterol
Intervention1 paper1 finding
- Cells1
Outcomes
1Cellular senescence
upin human cells1Very low certainty
1 study
Cellular senescence
upin human cells1Very low certainty
Desmosterol increases cellular senescence in human cells.
“desmosterol accumulation induced by DHCR24 deficiency promoted HUVECs senescence and inhibited caveolin-1/ERK signaling.”
CellsHUVEC
DHCR24 INSUFFICIENCY PROMOTES VASCULAR ENDOTHELIAL CELL SENESCENCE AND ENDOTHELIAL DYSFUNCTION · GSA 2024 abstract · 31 Dec 2024