Delta-sleep-inducing peptide

Intervention

2 papers5 findings

PubChemMeSH

  • 1 lab in 1 country
  • 1 finding against
  • Animals2

Outcomes

4

Lifespan

no changein mice1upin mice1+24% maximum life span

1 study
  1. Delta-sleep-inducing peptide has no effect on lifespan in mice.

    “did not influence mean life span”

    AnimalsDeltaran solved in 0.1 ml of saline2.5 microg/mouse (approximately 100 microg/kg)until their natural deathsfemalesn = 54

    Effect of delta-sleep inducing peptide-containing preparation Deltaran on biomarkers of aging, life span and spontaneous tumor incidence in female SHR mice

    Mechanisms of ageing and development1 Jun 2003

  2. Delta-sleep-inducing peptide extends lifespan in mice (+24.1% maximum life span).

    “increased by 17.1% life span of the last 10% of the survivors and by 24.1% maximum life span in comparison with the control group”

    AnimalsDeltaran solved in 0.1 ml of saline2.5 microg/mouse (approximately 100 microg/kg)until their natural deathsfemalesn = 54

    Effect of delta-sleep inducing peptide-containing preparation Deltaran on biomarkers of aging, life span and spontaneous tumor incidence in female SHR mice

    Mechanisms of ageing and development1 Jun 2003

Tumor incidence

downin mice1

1 study
  1. Delta-sleep-inducing peptide decreases tumor incidence in mice (2.6-fold decrease).

    “treatment with Deltaran significantly decreased total spontaneous tumor incidence (by 2.6-fold)”

    AnimalsDeltaran solved in 0.1 ml of saline2.5 microg/mouse (approximately 100 microg/kg)until their natural deathsfemalesn = 54

    Effect of delta-sleep inducing peptide-containing preparation Deltaran on biomarkers of aging, life span and spontaneous tumor incidence in female SHR mice

    Mechanisms of ageing and development1 Jun 2003

Chromosome aberrations

downin mice1−23%

1 study
  1. Delta-sleep-inducing peptide decreases chromosome aberrations in mice (-22.6%).

    “decreased by 22.6% the frequency of chromosome aberrations in bone marrow cells”

    AnimalsDeltaran solved in 0.1 ml of salinebone marrow2.5 microg/mouse (approximately 100 microg/kg)until their natural deathsfemalesn = 54

    Effect of delta-sleep inducing peptide-containing preparation Deltaran on biomarkers of aging, life span and spontaneous tumor incidence in female SHR mice

    Mechanisms of ageing and development1 Jun 2003

More on Chromosome aberrations

Body weight

downin mice1

1 study
  1. Delta-sleep-inducing peptide decreases body weight in mice.

    “decreased the body weight of mice”

    AnimalsDeltaran solved in 0.1 ml of saline2.5 microg/mouse (approximately 100 microg/kg)until their natural deathsfemalesn = 54

    Effect of delta-sleep inducing peptide-containing preparation Deltaran on biomarkers of aging, life span and spontaneous tumor incidence in female SHR mice

    Mechanisms of ageing and development1 Jun 2003

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