Cysteamine

1 paper studies it7 more mention it

PubChem ChEBI MeSH

1 trial, none about aging

Animals1

Development

Companies: Nacuity PharmaceuticalsPhase 1/2cystinosis

Trial sponsors

Nacuity Pharmaceuticals
Company1 trialPhase 1/28 people

Latest

1 paper in 12 months

Cell Biochemistry and BiophysicsAug 26

The Reductive Stress Nexus: Integrated Pathways of Metabolic Dysregulation, Senescence and Blood-Brain Barrier Failure in Neurodegenerative Disease and Brain Aging

ReviewNAD+ metabolism

Human Molecular GeneticsJan 23

Pre-clinical evaluation of cysteamine bitartrate as a therapeutic agent for mitochondrial respiratory chain disease

Experiments in animalsInterventions

Journal of Lipid ResearchNov 7

Lysosomal oxidation of LDL alters lysosomal pH, induces senescence, and increases secretion of pro-inflammatory cytokines in human macrophages

Experiments in cellsMechanisms

PLOS OneAug 3

Cigarette smoke induced autophagy-impairment regulates AMD pathogenesis mechanisms in ARPE-19 cells

Experiments in cellsInterventions

American Journal of Physiology Cell PhysiologyJul 15

Cigarette smoke-induced autophagy impairment accelerates lung aging, COPD-emphysema exacerbations and pathogenesis

Experiments in animalsMechanisms

Free Radical Biology & MedicineJul 11

Nicotine exposure induces bronchial epithelial cell apoptosis and senescence via ROS mediated autophagy-impairment

Experiments in animalsMechanisms

Free Radical Biology & MedicineJan 1

Increased transcription of the astrocyte gene GFAP during middle-age is attenuated by food restriction: implications for the role of oxidative stress

Experiments in ratsOxidative stress and ROS signaling

Journal of GerontologySep 1

Dietary restriction alone and in combination with oral ethoxyquin/2-mercaptoethylamine in mice

Experiments in miceDietary restriction