Cyc

1. Cyc has no effect on lifespan in yeast cells.

   “CYC did not extend the RLS of K6001 yeast mutants, such as Δsod1, Δsod2, Δcat, Δgpx, Δatg2, and Δatg32”

   Cellsin yeast mutants lacking SOD1, SOD2, CAT, GPX, ATG2, or ATG32

   β-Cyclocitral from Lavandula angustifolia Mill. Exerts Anti-Aging Effects on Yeasts and Mammalian Cells via Telomere Protection, Antioxidative Stress, and Autophagy Activation

   Antioxidants (Basel, Switzerland)·Jun 12, 2024

2. Cyc extends lifespan in yeast cells.

   “This molecule extended the yeast lifespan”

   Cellsreplicative and chronological lifespan

   β-Cyclocitral from Lavandula angustifolia Mill. Exerts Anti-Aging Effects on Yeasts and Mammalian Cells via Telomere Protection, Antioxidative Stress, and Autophagy Activation

   Antioxidants (Basel, Switzerland)·Jun 12, 2024

1. Cyc activates autophagy in yeast cells.

   “CYC enhanced autophagic flux and free green fluorescent protein (GFP) expression in the YOM38-GFP-ATG8 yeast strain.”

   Cells

   β-Cyclocitral from Lavandula angustifolia Mill. Exerts Anti-Aging Effects on Yeasts and Mammalian Cells via Telomere Protection, Antioxidative Stress, and Autophagy Activation

   Antioxidants (Basel, Switzerland)·Jun 12, 2024

More on Autophagy

1. Cyc increases survival rate in yeast cells.

   “CYC improved the survival rate of BY4741 yeast under oxidative stress induced by 6.2 mM H2O2”

   Cells6.2 mM H2O2

   β-Cyclocitral from Lavandula angustifolia Mill. Exerts Anti-Aging Effects on Yeasts and Mammalian Cells via Telomere Protection, Antioxidative Stress, and Autophagy Activation

   Antioxidants (Basel, Switzerland)·Jun 12, 2024

1. Cyc decreases cellular senescence in yeast cells.

   “inhibited etoposide (ETO)-induced cell senescence.”

   Cellsetoposide-induced

   β-Cyclocitral from Lavandula angustifolia Mill. Exerts Anti-Aging Effects on Yeasts and Mammalian Cells via Telomere Protection, Antioxidative Stress, and Autophagy Activation

   Antioxidants (Basel, Switzerland)·Jun 12, 2024

More on Cellular senescence

1. Cyc predicts senescence-associated beta-galactosidase in humans.

   “When applied to small fragments of clinical human liver samples via simple ex vivo immersion, CyC readily detects β-Gal activity.”

   Humansliver

   Liver-Targeted Triple-Modal Molecular Probe for Visualization of Aging Marginal Donor Livers

   Analytical chemistry·Jul 12, 2026

2. Cyc predicts senescence-associated beta-galactosidase in mice.

   “CyC produces a turn-on NIRF/PA response accompanied by a distinct blue-to-green color change visible to the naked eye.”

   Animalsliver

   Liver-Targeted Triple-Modal Molecular Probe for Visualization of Aging Marginal Donor Livers

   Analytical chemistry·Jul 12, 2026

More on Senescence-associated beta-galactosidase