Cu-sn dual-atom nanozyme cloaked with young cell hybrid membrane

1. Cu-sn dual-atom nanozyme cloaked with young cell hybrid membrane decreases ER unfolded protein response in mouse cells.

   “The composite nanozyme effectively mitigates intracellular oxidative stress and ERS in aged cells, rescuing their osteogenic and angiogenic potential.”

   Cells

   Orbital hybridization-mediated nanozymes reverse cellular senescence for aged bone regeneration

   Biomaterials·5 Jun 2026

More on ER unfolded protein response

1. Cu-sn dual-atom nanozyme cloaked with young cell hybrid membrane decreases oxidative stress and ROS signalling in mouse cells.

   “The composite nanozyme effectively mitigates intracellular oxidative stress and ERS in aged cells, rescuing their osteogenic and angiogenic potential.”

   Cells

   Orbital hybridization-mediated nanozymes reverse cellular senescence for aged bone regeneration

   Biomaterials·5 Jun 2026

More on Oxidative stress and ROS signalling

1. Cu-sn dual-atom nanozyme cloaked with young cell hybrid membrane increases bone volume fraction in mice (1.7-fold).

   “increasing the bone volume fraction (BV/TV) by 1.7-fold and significantly enhancing new bone mineralization.”

   Animalsjawbone defectbone

   Orbital hybridization-mediated nanozymes reverse cellular senescence for aged bone regeneration

   Biomaterials·5 Jun 2026