Cma activators

Intervention1 paper2 findings

  • Animals1

Outcomes

2

Pulmonary fibrosis severity

downin mice1Very low certainty

1 study
  1. Cma activators decrease pulmonary fibrosis severity in mice.

    AnimalsPulmonary fibrosis mouse modellung

    Protein recycling decline hinders senescent cell clearance in mice · Nature aging · 5 Oct 2026

Senescent cell burden

downin mice1Very low certainty

1 study
  1. Cma activators decrease senescent cell burden in mice.

    Animals

    Protein recycling decline hinders senescent cell clearance in mice · Nature aging · 5 Oct 2026

Senescent cell burden →

Latest

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Nature AgingAnimals

Protein recycling decline hinders senescent cell clearance in mice

In experiments in mice, blocking a protein-recycling pathway in immune cells increased the build-up of senescent cells, which had stopped dividing.In experiments in mice, blocking a protein-recycling pathway in immune cells increased the build-up of senescent cells, which had stopped dividing.